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Borderline Phyllodes Tumor with an Incidental Invasive Tubular Carcinoma and Lobular Carcinoma In Situ Component: A Case Report
Authors:Sean Quinlan-Davidson  Nicole Hodgson  Leela Elavathil  Tang Shangguo
Affiliation:Department of Radiation Oncology, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada.;1.Department of Surgery, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada.;2.Department of Pathology, Juravinski Hospital, McMaster University, Hamilton, Ontario, Canada.;3.Department of Anatomical Pathology, McMaster University Medical Centre, Hamilton, Ontario, Canada.
Abstract:Phyllodes tumors are an infrequent breast tumor presentation. A phyllodes tumor with a synchronous invasive ductal carcinoma is rarely described and has never been reported with lobular carcinoma in situ component. A 53-year-old female presented with a nine-year history of twice core biopsy proven fibroadenoma. After an increase in the tumor''s growth velocity it was decided upon to undergo an excisional biopsy. Microscopic examination of the well-circumscribed pale-tan mass found focal areas of leaf like architecture with variable number of mitoses present, representing a phyllodes tumor of borderline malignant potential. Incidentally, at one edge of the mass was found a tubular carcinoma and lobular carcinoma in situ components. Thorough, routine follow-up of patients with biopsy proven benign breast masses is important to finding a masked malignant component.
Keywords:Breast neoplasms   Breast screening   Fibroepithelial tumor   Mammography
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