| 清肾颗粒对腺嘌呤所致慢性肾功能衰竭大鼠血清甲状旁腺素的影响 |
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| 引用本文： | 耿静,王亿平. 清肾颗粒对腺嘌呤所致慢性肾功能衰竭大鼠血清甲状旁腺素的影响[J]. 安徽医药, 2007, 11(8): 683-685 |
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| 作者姓名： | 耿静 王亿平 |
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| 作者单位： | 安徽省淮北市人民医院中医科,安徽,淮北,235000;安徽中医学院第一附属医院肾病科,安徽,合肥,230000 |
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| 摘 要： | 目的观察清肾颗粒对慢性肾功能衰竭大鼠血清甲状旁腺素水平的干预作用。方法将腺嘌呤摄入量按每日300 mg.kg-1体重给予,制作慢性肾功能衰竭动物模型。用清肾颗粒(每ml含生药0.5 g)治疗,用保肾康(6 g.L-1)作对照。检测大鼠血清甲状旁腺素、肌酐、尿素氮和24 h尿蛋白定量及肾脏病理改变。结果造模各组大鼠上述指标和正常组相比明显增加(P<0.001)。治疗后上述指标和模型组相比明显减少(P<0.001)。结论清肾颗粒可显著降低CRF大鼠血清上述指标,其效果优于保肾康。
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| 关 键 词： | 慢性肾功能衰竭 清肾颗粒 甲状旁腺素 实验研究 |
| 修稿时间： | 2007-04-24 |
Experimental study of Qingshen granule on the level of serum PTH in rats with chronic renal failure |
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| GENG Jing,WANG Yi-ping. Experimental study of Qingshen granule on the level of serum PTH in rats with chronic renal failure[J]. Anhui Medical and Pharmaceutical Journal, 2007, 11(8): 683-685 |
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| Authors: | GENG Jing WANG Yi-ping |
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| Affiliation: | 1.Department of Traditional Chinese Medicine of Renmin Hospital of Huaibei City,Huaibei 235000;2.Department of Renopathy of the First Hospital Affiliated with Anhui College of Traditional Chinese Medicine,Hefei 230000 |
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| Abstract: | |
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| Keywords: | chronic renal failure Qingshen granule PTH experimental research |
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