| 绞股蓝泡服对实验性高脂血症及血液流变学的影响 |
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| 引用本文： | 马平勃, 朱全红, 黄中伟. 绞股蓝泡服对实验性高脂血症及血液流变学的影响[J]. 中国现代应用药学, 2005, (6): 454-455. |
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| 作者姓名： | 马平勃 朱全红 黄中伟 |
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| 作者单位： | 1. 南方医科大学附属南方医院药学部,广东,广州,510515
2. 南方医科大学中医药学院,广东,广州,510515 |
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| 摘 要： | 目的 探讨绞股蓝冲泡灌胃给药对实验性高脂血症及血液流变学的影响，方法 在给新西兰健康兔喂饲高脂饲料的同时，泡服绞股蓝微粉。结果 绞股蓝微粉泡服具有显著地降脂、降黏、改善血液流变性、红细胞变形性和微循环等作用。结论 表明绞股蓝微粉泡服是一种既能降脂又能改善血液流变学的药物。
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| 关 键 词： | 绞股蓝 高脂血症 血液流变学 |
| 文章编号： | 1007-7693（2005）06-0454-02 |
| 收稿时间： | 2004-03-24 |
| 修稿时间： | 2004-03-24 |
Effects of Gynostemma pentaphyllum on the blood-lipid and hemorheology in hyperlipidemia rabbits |
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| MA Ping-bo, ZHU Quan-hong, HUANG Zhong-wei. Effects of Gynostemma pentaphyllum on the blood—lipid and hemorheology in hyperlipidemia rabbits[J]. Chinese Journal of Modern Applied Pharmacy, 2005, (6): 454-455. |
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| Authors: | MA Ping-bo~ ZHU Quan-hong~ HUANG Zhong-wei~ |
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| Affiliation: | 1. Department of Pharmacy, Nanfang hospital,Southern Medical University, Guangzhou 510515, China; 2. Department of TC M , Southern Medical University, Guangzhou 510515 |
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| Abstract: | OBJECTIVE To observe the effects of Gynostemma pentaphyllum on the blood-lipid and hemorheology in hyperlipidemia rabbits.METHODS Total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL),high density lipoprotein,parameters of hemorheology in serum were determined after the hyperlipidemia rabbits were established and administrated with Gynostemma pentaphyllum. RESULTS Hyperlipidemia rabbits'models were established by feeding hyperlipi-diet.The TC,TG LDL,HDL were decreased remarkably,the parameters of hemorheology,whole blood viscosity,plasma viscosity,RBC accumulation and RBC deformation were reduced obviously by Gynostemma pentaphyllum.CONCLUSION The results show that Gynostemma pentaphyllum can obviously decrease the blood-lipid and improve hemorheology in hyperlipidemia rabbits. |
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| Keywords: | Gynostemma pentaphyllum hyperlipidemia hemorheology |
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