| 寨卡病毒包膜prM-E蛋白的结构和功能分析 |
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| 引用本文： | 卢昌,李娜,薛璞,李楠,陈平. 寨卡病毒包膜prM-E蛋白的结构和功能分析[J]. 中国人兽共患病杂志, 2017, 0(1): 81-84. DOI: 10.3969/j.issn.1002-2694.2017.01.015 |
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| 作者姓名： | 卢昌 李娜 薛璞 李楠 陈平 |
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| 作者单位： | 1. 河北安宇科技有限公司,廊坊 065500;嘉兴安宇生物科技有限公司,嘉兴 314000;2. 河北安宇科技有限公司,廊坊,065500;3. 嘉兴安宇生物科技有限公司,嘉兴,314000 |
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| 摘 要： | 包膜蛋白prM-E是黄病毒的主要结构蛋白,含有许多病毒的表面抗原,与病毒的致病力和宿主嗜性有关,但目前对寨卡病毒的prM-E蛋白研究很少,作者利用生物信息学方法对寨卡病毒的E蛋白进行了预测,重点阐述了prM-E蛋白在黄病毒形成病毒样颗粒过程中的应用,并对寨卡病毒病毒样颗粒的应用进行了展望。
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| 关 键 词： | ZIKV 登革热病毒 包膜蛋白prM-E |
Function and structure analysis of premembrane and envelope proteins of Zika virus |
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| LU Chang,LI Na,XUE Pu,LI Nan,CHEN Ping. Function and structure analysis of premembrane and envelope proteins of Zika virus[J]. Chinese Journal of Zoonoses, 2017, 0(1): 81-84. DOI: 10.3969/j.issn.1002-2694.2017.01.015 |
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| Authors: | LU Chang LI Na XUE Pu LI Nan CHEN Ping |
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| Abstract: | The premembrane and envelope proteins (prM-E),which contains the mainly protective antigen related with virulence and tropism,are the primary structural protein of flavivirus.However,prM-E in ZIKV is rarely understood.We have analyzed the structure and biological effects of prM-E in ZIKV by bionformatics methods.The prM-E proteins virus-like particles of dengue virus was introduced in the present.Then,the prM-E proteins virus like particles of ZIKV was prospected. |
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| Keywords: | ZIKV dengue virus premembrane and envelope proteins |
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