| 秋水仙碱在冠状动脉粥样硬化性心脏病防治中的研究进展与争议 |
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| 引用本文： | 吉蓉,寿锡凌. 秋水仙碱在冠状动脉粥样硬化性心脏病防治中的研究进展与争议[J]. 心血管病学进展, 2022, 0(1): 60-63 |
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| 作者姓名： | 吉蓉 寿锡凌 |
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| 作者单位： | 西安医学院;陕西省人民医院心血管内科 |
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| 摘 要： | 既往大量研究表明炎症在冠状动脉粥样硬化性心脏病(冠心病)的发生和发展中扮演了重要角色,抗炎治疗一直是冠心病研究领域的热点.近年几项大型临床研究发现秋水仙碱可预防冠心病患者不良心血管事件的发生,改善冠心病患者的预后,但同时秋水仙碱在临床应用中也存在诸多争议.现就秋水仙碱在冠心病防治中的最新研究进展及存在的争议做一综述.
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| 关 键 词： | 炎症 冠状动脉粥样硬化性心脏病 秋水仙碱 |
Research Progress and Controversy of Colchicine in Prevention and Treatment of Coronary Atherosclerotic Heart Disease |
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| JI Rong,SHOU Xiling. Research Progress and Controversy of Colchicine in Prevention and Treatment of Coronary Atherosclerotic Heart Disease[J]. Advances in Cardiovascular Diseases, 2022, 0(1): 60-63 |
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| Authors: | JI Rong SHOU Xiling |
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| Affiliation: | (Xi’an Medical University,Xi’an 710068,Shaanxi,China;Department of Cardiology,Shaanxi Provincial People’s Hospital,Xi’an 710068,Shaanxi,China) |
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| Abstract: | A large number of previous studies have shown that inflammation plays an important role in the occurrence and development of coronary atherosclerotic heart disease(CHD),and anti-inflammatory therapy has always been a hot spot in the field of CHD.In recent years,several large-scale clinical studies have found that colchicine can prevent adverse cardiovascular events in patients with CHD and improve the prognosis of patients with CHD.However,there are also many controversies in the clinical application of colchicine.This article reviews the latest research progress and existing controversies of colchicine in the prevention and treatment of CHD. |
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| Keywords: | Inflammation Coronary atherosclerotic heart disease Colchicine |
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