2015年四川省胃癌和食管癌发病及死亡分析

目的分析2015年四川省上消化道恶性肿瘤(胃癌和食管癌)发病、死亡和潜在减寿情况。方法收集四川省24个肿瘤登记处上报的2015年恶性肿瘤发病、死亡及人口资料。提取ICD-10编码C15-C16选择食管癌、胃癌的发病和死亡数据,用SAS 9.3软件分别计算性别、年龄别发病和死亡的粗率、标化率、构成比、累积率(0~74岁)、潜在减寿年数(potential years of life lost,PYLL)、潜在减寿率(potential years of life lost rate,PYLLR)和平均减寿年(average years of life lost,AYLL)。标准人口采用2000年全国普查人口年龄构成和Segi’s世界人口年龄构成。结果2015年四川省肿瘤登记地区食管癌和胃癌发病率分别为29.29/10万和28.60/10万,分别居发病第3位和第4位;胃癌和食管癌死亡率分别为23.90/10万和22.20/10万,分别居死亡第3位和第4位;根据上消化道恶性肿瘤发病率和死亡率的年龄性别分布,男女性45岁后发病率和50岁后死亡率均显著升高;无论城乡,男性食管癌和胃癌各项发病和死亡指标均高于女性。农村地区人群食管癌和胃癌疾病负担高于城市。食管癌潜在减寿年数为23399人年,平均减寿年数为15.41年,减寿率为1.92‰;胃癌潜在减寿年数为25390人年,平均减寿年数为16.74年,减寿率为2.09‰。结论四川省食管癌和胃癌发病与死亡水平相对较高,男性为食管癌和胃癌的高发人群,45岁以上的中老人群是上消化道恶性肿瘤高风险人群,农村地区人群的上消化道肿瘤疾病负担高于城市。

The Incidence And Mortality of Upper Gastrointestinal Tumors in Sichuan Province in 2015

Objective To analyze the incidence and morbidity of gastrointestinal tumors in Sichuan Province in 2015.Methods Data of gastrointestinal tumors incidence and mortality were collected from 24 tumor registries in Schuan Province in 2015.ICD-10 code(i.e.,C15-C16)was used to extract data of esophageal and gastric cancer morbidity and mortality.SAS 9.3 software was used to calculate the sex,age-specific crude incidence and mortality,standardized rate,composition ratio and cumulative rate(0-74 years old),potential years of life(PYLL),potential years of life lost rate(PYLLR),and average years of life lost(AYLL).The age composition of the 2000 national census population and the age composition of the world population of Segi’s were adopted to calculate standardized ncidence and mortality.Results In 2015,the crude incidence rates of esophageal and gastric cancer were 29.29/10^5 and 23.90/10^5,ranking in the 3^rd and 4^th place of the incidence of cancer,respectively.The crude mortality rates of gastric and esophageal cancer were23.90/105 and 22.20/105,ranking in the 3rd and 4th of the mortality of cancer,respectively.As for the age and sex distribution,the incidence increased significantly in both men and women aged above 45 years.Similarly,the mortality increased significantly in both men and women aged above 50 years.In both urban and rural areas,the incidence and mortality indicators of esophageal cancer and gastric cancer were higher in males than those in females.The disease burden of upper gastrointestinal malignancies in rural areas is higher than that in urban areas.The potential life expectancy of esophageal cancer was 23399 human years,the mean life expectancy was 15.41 years,and the life expectancy rate was 1.90‰.The potential life expectancy of gastric cancer was25390 years,the mean life expectancy was 16.74 years,and the life expectancy was 2.09‰.Conclusion The incidence and mortality of esophageal and gastric cancer in Sichuan Province is relatively high.Men and older adults over the age of 45 years are at high risk for upper gastrointestinal malignancy.The disease burden of upper gastrointestinal malignancies in rural areas is higher than that in urban areas.