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口服糖皮质激素治疗AECOPD的疗效观察
引用本文:左美容.口服糖皮质激素治疗AECOPD的疗效观察[J].临床肺科杂志,2010,15(5):623-624.
作者姓名:左美容
作者单位:衡阳,衡阳市第三人民医院肺科,湖南,421101
摘    要:目的观察口服糖皮质激素对AECOPD的疗效。方法将86例AECOPD住院患者随机分为两组:治疗组和对照组。对照组42例,给予控制性氧疗,敏感的抗生素和支气管舒张剂。治疗组44例,除上述治疗外,口服泼尼松30 mg/d,连服10天。观察肺功能FEV1、血气分析PaO2、呼吸困难改善天数和不良反应。结果治疗组FEV1为1.01±0.23 L,比对照组0.88±0.26 L明显提高(P0.05)。治疗组PaO2为74±11 mmHg,较对照组73±12 mmHg明显提高(P0.05)。呼吸困难改善天数治疗组2.7±1.2天较对照组6.0±2.0天有明显缩短。不良反应无明显差别。结论口服糖皮质激素可改善AECOPD肺功能及临床结果,建议短期使用全身糖皮质激素。

关 键 词:AECOPD  糖皮质激素  治疗

The observation on effects of oral glucocorticoid in the treatment of chronic obstructive pulmonary disease with acute exacerbation
ZUO Mei-rong.The observation on effects of oral glucocorticoid in the treatment of chronic obstructive pulmonary disease with acute exacerbation[J].Journal of Clinical Pulmonary Medicine,2010,15(5):623-624.
Authors:ZUO Mei-rong
Institution:ZUO Mei-rong.( The 3rd People's Hospital of Hengyang, Hengyang 421101, China )
Abstract:Objective To observe the effect of oral glucocorticoids in treating chronic obstructive pulmonary disease with acute exacerbation(AECOPD).Methods 86 cases of AECOPD patients were randomly divided into 2 groups:treatment group and the control group.42 cases of the control group were given controlled oxygen therapy,antibiotics and sensitive Bronchodilator agents.44 cases of the treatment group,besides the above-mentioned treatment,were given oral prednisone 30 mg/d,even serving for 10 days.Pulmonary function ...
Keywords:AECOPD  glucocorticoid treatment  
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