Phosphomonoester concentrations differ between chronic lymphocytic leukemia cells and normal human lymphocytes |
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| Authors: | Franks Suzanne E Smith Mitchell R Arias-Mendoza Fernando Shaller Calvin Padavic-Shaller Kristen Kappler Francis Zhang Yun Negendank William G Brown Truman R |
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| Affiliation: | NMR and Medical Spectroscopy, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA. |
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| Abstract: | Levels of phospholipid-related metabolites of chronic lymphocytic leukemia lymphocytes (CLL) and normal human lymphocytes were quantified using phosphorus magnetic resonance spectroscopy. The CLL cells versus normal lymphocytes showed significant increases of phosphoethanolamine(Etn-P) (8.11+/-2.10 mean+/-S.E., micromol/g wet weight, n=12 versus 3.63+/-1.10, n=3, P
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