妊娠多形疹26例临床分析

目的探讨妊娠多形疹对孕妇和胎儿的影响。方法回顾性分析26例妊娠多形疹孕妇的体重、性激素水平、免疫学指标及新生儿评分等临床资料,并以26例同期健康孕妇为对照。结果观察组孕妇体重71.5～98.6(81±11.21)kg,对照组为65.3～88.6(71±10.62)kg,两组孕妇平均体重比较,差异有统计学意义(P<0.05);β-绒毛膜促性腺激素(β-hCG)和游离雌三醇(uE3)水平观察组分别为368±47和65.3±7.96,对照组分别为354±41和63.5±6.54,两组差异均无统计学意义(P均>0.05);血液IgA、IgM、IgG及循环免疫复合物(CIC)水平观察组依次为1.76±0.6、11.47±0.49、12.89±1.15和25.86±3.23,对照组依次为1.62±0.54、11.68±0.38、12.33±1.21和24.13±3.56,差异均无统计学意义(P均>0.05);新生儿平均体重及1分钟Apgar评分比较,差异均无统计学意义(P均>0.05)。结论妊娠多形疹对孕妇和胎儿无明显不良影响。

Clinical Analysis of 26 Cases With Polymorphic Eruption of Pregnancy

Objective To explore the effect of polymorphic eruption on pregnancy women and fetus.Methods The clinical data about 26 cases and healthy control were analyzed,retrospectively.Results The weight of observation group was 71.5～98.6(81±11.21)kg;the control group was 65.3～88.6(71±10.62)kg,there was a significant difference between the groups(P<0.05).Levels of human chorionic gonadotropin(hCG),human unconjugateb-asttriol(uE3),in observation group were 368±47 and 65.3±7.96,354±41 and 63.5±6.54 in control group respectively,there were no significant difference between the two groups(P>0.05).The bloodimmunoglobulinA(sIgA)、Immuno-globulinG(sIgG)、immunoglobulinM(sIgM) and circulating immune complexes(CIC) were 1.76±0.6、11.47±0.49、12.89±1.15 and 25.86±3.23 in the observation group,and 1.62±0.54、11.68±0.38、12.33±1.21 and 24.13±3.56 in control group respectively,the difference were no statistical significant(P>0.05).The average weight of the newborn and Apgar were no statistical significant different between two groups(P>0.05).Conclusion Polymorphic eruption was no impact on preqnancy women and fetus.