不同材料预防硬膜粘连对脊髓电生理的影响

目的：探讨脂肪组织向椎管嵌入的原因及导致神经电生理异常的机理。方法：以24只SD大鼠为实验对象，随机分为高分子纤维素，游离脂肪移植，带蒂脂肪移植和对照组四组，每组6只动物。通过术前、术后即刻及术后8周行光镜、脊髓节段性诱发电位（SCEP）和腰骶运动神经传导速度（LSCV）检测，观察了椎板切除手术为防止硬膜粘连所充填的上述不同材料对神经传导机能的影响。结果：椎板切除手术可酿成一过性脊髓传导异常。术后8周，游离及带蒂脂肪移植不仅可见移植物向椎管内嵌入，致使硬膜囊及神经根受压的组织形态学变化，尚可使脊髓及神经传导机能障碍进一步加重。结论：脂肪组织移植用于预防椎板切除术后硬膜周围纤维化应慎重。

Spinal Cord and Never Roots Conduction Implicated by Laminectomy and Various Materials in Dural Space:An Experimental Study in Rats

Objective: To determine the electrophysiological changes of spinal cord.Methods:Twenty four SD rats were divided randomly into four groups: poly carboxymethy cellulose(PCMC);Free fat (FF);Pedicle fat(PF) and contral,6 rats in every group.The changes were measured,by double blind protocal,before,after and electrophysiological examination.Results:Laminectomy may result in transent abnormality of spinal cord electrophysiology.However,for FF and PF groups,there were not only a histological presentation of transplanted fat extended into or compressed spinal cord and never roots,but also the spinal cord and never roots conduct were implicated in the late period.The mechanism of the complications were researched in the study.Conclusions:The method of transplanted fat to prevent fiborosis around the sclcromeainx should be prudent.