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低分子量肝素钙对不稳定性心绞痛的疗效及QTcd改善的临床研究
引用本文:李予文,牛新丽,刘伟利,赵桂叶,许世然.低分子量肝素钙对不稳定性心绞痛的疗效及QTcd改善的临床研究[J].中国医药导刊,2005,7(1):41-42.
作者姓名:李予文  牛新丽  刘伟利  赵桂叶  许世然
作者单位:新乡市第一人民医院心内科,新乡,453000
摘    要:目的:观察低分子量肝素(LMWH)和普通肝素对不稳定性心绞痛(UA)的疗效和QTcd的改善程度.方法:将145例住院的UA患者随机分为2组,分别用LMWH和普通肝素治疗1周.结果:LMWH治疗组有效率:94.4%,普通肝素对照组组81.6%(P<0.01);QTcd的改善LMWH治疗组也明显优于普通肝素对照组(P<0.01).结论:早期应用LMWH治疗UA可以改善预后,降低副反应的发生率.

关 键 词:低分子量肝素  不稳定性心绞痛  QT离散度

Clinical Investigation about Low- Molecular- Weight Heparin in Unstable Angina and QTcd
Li Yu - wen,Niu Xin - li,Liu Wei - li,et al..Clinical Investigation about Low- Molecular- Weight Heparin in Unstable Angina and QTcd[J].Chinese Journal of Medicinal Guide,2005,7(1):41-42.
Authors:Li Yu - wen  Niu Xin - li  Liu Wei - li  
Abstract:Objective: To observe the effect of Low - molecular - weight heparin (IMWH) on unstable angina (UA) and the improvement of QTcd.Methods: 145 UA patients were randomized into two groups and treated with LMWH and general sodium heparin res pertivdy for 1 week. Results: The effective rate was 94.4% in group of LMWH and 81.6% in the general sodium heparin group.The amelioration of QTcd in LMWH group was obvoursly advantaged to that of the other group (P < 0.01). Conclution: Early administration of LMWH in UA can improve the prognosis and reduce the incidence of adverse.
Keywords:Low- molecular - weight heparin  unstable angina  QTcd
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