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Chemical Constituents of Whole Plant of Polygonum chinese L. var hispidum Hook.f.

??OBJECTIVE To investigate the antioxidant activities and chemical constituents of Polygonum chinese L. var hispidum Hook.f.METHODS The compounds were isolated by chromatographic techniques with silica gel, Sephadex LH-20 and semi-preparative HPLC. Their structures were identified by analysis of physical and spectral data, and confirmed by comparison of their spectral data with the reported values in the literature or those of authentic samples. The antioxidant activities of the extractions of Polygonum chinese L. var hispidum Hook.f. were evaluated by oxygen radical absorption capacity(ORAC) assay. RESULTS Fifteen compounds were isolated and identified as isopsoralen(1), 2,3,4,6,7-pentamethoxy-9,10-dihydrophenanthrene(2), 1,5,7-tri hydroxy-3-methyl-anthraquinone(3), quercetin(4), gallincin(5), gallic acid(6), heneicosanoic acid(7), nonadecanoic acid(8), arachidic acid(9), triacontanoic acid(10), tetracosanoic acid(11), palmitic acid(12), lacceroic acid(13), ??-sitosterol(14), and daucosterol(15), respectively. Ethyl acetate extracts had stronger antioxidant activities. CONCLUSION All compounds are isolated from the species for the first time, and compound 2 is obtained from this genus for the first time