|
|||||
|
|
| ˫�������ز����칹���ת���뺬���ⶨ�������о� | |
| 引用本文： | ����,����,������,����,����. ˫�������ز����칹���ת���뺬���ⶨ�������о�[J]. 中国药学杂志, 2016, 51(5): 396-399. DOI: 10.11669/cpj.2016.05.012 |
| 作者姓名： | ���� ���� ������ ���� ���� |
| 作者单位： | 1.?????????????????о??,????401121; 2.?????????????????????????????о?????,????401121 |
| 摘 要： | |
| 关 键 词： | ????????? ??Ч??????? ???????? ??????? ?????? |
The Research of Epimers Conversion and the an HPLC Method for Content Determination of Dihydroartemisinin |
|
| LIANG Jing,ZHOU Lin,LUO Li-jun,ZHANG Mian,ZENG Ling-gao. The Research of Epimers Conversion and the an HPLC Method for Content Determination of Dihydroartemisinin[J]. Chinese Pharmaceutical Journal, 2016, 51(5): 396-399. DOI: 10.11669/cpj.2016.05.012 | |
| Authors: | LIANG Jing ZHOU Lin LUO Li-jun ZHANG Mian ZENG Ling-gao |
| Affiliation: | 1. Chongqing Institute for Food and Drug Control, Chongqing 401121, China; 2. Chongqing Engineering Research Center for Pharmaceutical Process and Quality Control, Chongqing 401121, China |
| Abstract: | ??OBJECTIVE To establish the content determination method for dihydroartemisinin(DHA). METHODS The high performance liquid chromatography was carried out on a column packed with octadecylsilane bonded silica gel (CAPCELL PAK C18 MG??,4.6 mm??100 mm,3 ??m), using a mixture of acetonitrile-water (60??40) as the mobile phase.Dimethylsulfoxide was chosen as the solvent for the DHA bulk drug.The detection wavelength was set at 216 nm and the flow rate was 0.6 mL??min-1. RESULTS The linear range of DHA calibration curve was 0.505 35-50.535 ??g (r=0.999 9). CONCLUSION Compared with the method included in ChP, the precision of the established content determination method is improved significantly. It is accurate, reliable, convenient, and has good reproducibility for content determination of DHA. |
| Keywords: | |
| 点击此处可从《中国药学杂志》浏览原始摘要信息 | |
| 点击此处可从《中国药学杂志》下载全文 | |