51例烧伤伴急性肾衰竭患者死亡危险因素分析

目的探讨合并急性肾衰竭的烧伤患者的临床特点及死亡危险因素。方法回顾性分析51例烧伤伴急性肾衰竭患者的临床资料．对死亡的相关因素进行单因素和多因素分析。结果5l例患者的存活率为56．9％（29／51），病死率为43．1％（22／51）。存活组和死亡组的人院距烧伤时间，吸人性烧伤构成比，烧伤面积，少尿构成比，血肌酐峰值及终点值．白蛋白水平，肌酸激酶水平，合并多器官功能衰竭、脓毒血症、烧伤休克的构成比，以及急性。肾损伤分级的差异有统计学意义（P〈0．05）。烧伤面积、少尿、肌酸激酶水平是死亡的独立危险因素。结论合并急性肾衰竭的烧伤重症患者的病死率高．烧伤面积、尿量、肌酸激酶水平等因素影响患者预后。

Analysis of death-related risk factor in 51 burn patients with acute renal failure

Objective To analyze the clinical characteristics and death-related risk factors of burn patients with acute renal failure （ARF） in bum intensive care unit （BICU）. Methods Clinical data of 51 burn patients with ARF were retrospectively analyzed, and the death-risk factors were analyzed by univariate and multivariate analysis. Results Among the 51 patients, the survival rate was 56.9%（29/51）, the mortality was 43.1%（22/51）. Time from burn to admission, the ra- tio of patients with inhalation injury, total-body surface area of burn, the ratio of oligouria, peak serum creatinine and end- point serum creatinine, serum albumin level, ereatine kinase level, the ratio of multiple organ dysfunction syndrome （MODS）, the ratio of septicemia, and the ratio of burn shock and classification of acute kidney injury were the factors that affected the prognosis by univariate analysis （P 〈 0.05）. The total-body surface area of burn, the ratio of oligouria, creatine kinase level were the factors that affected the prognosis by multivariate analysis （P 〈 0.05）. Conclusion The mortality of burn patients with ARF is high, total-body surface area of burn, oligouria,and creatine kinase level can affect the progno- sis.