醒脑静治疗脑出血60例临床观察

目的:观察醒脑静治疗急性脑出血的临床疗效。方法:120例脑出血患者随机分为两组,对照组根据出血量给予不同剂量的脱水药,控制血压及血糖,并给予脑细胞活化剂及对症治疗。治疗组在对照组基础上,给予醒脑静10ml加入0.9%生理盐水250ml静脉滴注,1次/d,共14d。采用神经功能缺损评分中国卒中量表(CSS),于治疗前与治疗后14d、28d对两组患者进行神经功能缺损评分。结果:患者经上述治疗后,其治疗组CSS由治疗前的(18.9±6.10)分下降到治疗后14d的(15.1±4.16)分,治疗后28d的(10.9±3.72)分;而对照组CSS由治疗前的(19.2±8.51)分下降到治疗后14d的(17.3±6.80)分,治疗后28d的(15.7±5.87)分,两组组内比较差异有统计学意义(P<0.05和P<0.01),两组间比较差异有统计学意义(P<0.05)。两组均无明显不良反应。结论:醒脑静能改善急性脑出血患者的神经功能缺损症状。

Clinical Therapeutic Effects of Xingnaojing Injection in Treatment of Acute Cerebral Hemorrhage

Objective:To study the clinical therapeutic effects of Xingnaojing injection in the treatment of acute cerebral hemorrhage. Methods:120 patients with acute cerebral hemorrhage were randomly divided into two equal groups:the trial group and control group. Osmotic diuretics,antihypertensives,antidiabetics, brain cell activators and remedies for symptomatic treatment in different doses were used in the control group according to the extent of the cerebral hemorrhage. Based on these managements,the trial group were given each 10ml Xingnaojing of dissolved in 250ml of 0.9% sodium chloride solution administered by intravenous instillation qd for 14 consecutive days.The score of nervous function defect of both groups were carried out on 14th day and 28th day after the termination of treatment course with China stroke scale (CSS). Results:The CSS score decreased from(18.9 ±6.10) to (15.1±4.16) on 14th day,to (10.9±3.72) on 28th day in the trial group,and changed from (19.2±8.51)to (17.3±6.80) on 14th day,to (15.7±5.87) on 28th day in the control group after the treatment. The differences have statistically significances(P<0.05,P<0.01). No adverse reactions were encountered in both groups. Conclusion: Xingnaojing can improve the nervous function effectively in patients with acute cerebral hemorrhage.