Roles of liver innate immune cells in nonalcoholic fatty liver disease |
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| Authors: | Yu-Tao Zhan and Wei An |
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| Affiliation: | Yu-Tao Zhan, Department of Gastroenterology and Hepatology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;Wei An, Department of Cell Biology, Capital Medical University, Beijing 100069, China |
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| Abstract: | Nonalcoholic fatty liver disease (NAFLD) has become the most common liver disease in the United States and other developed countries and is expected to increase in the next few years. Emerging data suggest that some patients with NAFLD may progress to nonalcoholic steatohepatitis (NASH), cirrhosis and even hepatocellular carcinoma. NAFLD can also promote the development and progression of disease in other organ systems, such as the cardiovascular and endocrine (i.e. diabetes) systems. Thus, understanding th... |
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| Keywords: | Innate immune cells Nonalcoholic fatty liver disease Kupffer cell Natural killer T cell Natural killer cell |
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