ApoB-100, ApoE and CYP7A1 gene polymorphisms in Mexican patients with cholesterol gallstone disease |
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| Authors: | S��nchez-Cu��n Jaime Aguilar-Medina Maribel Ar��mbula-Meraz Eliakym Romero-Navarro Jos�� Granados Julio Sicairos-Medina Laura Ramos-Pay��n Rosal��o |
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| Affiliation: | Sánchez-Cuén Jaime; División de Gastroenterología; Hospital Regional ISSSTE; Culiacán; Sinaloa 80230; México Aguilar-Medina Maribel; Arámbula-Meraz Eliakym; Romero-Navarro José; Sicairos-Medina Laura; Ramos-Payán Rosalío; Facultad de Ciencias Químico Biológicas; Doctorado en Biotecnología y Maestría en Ciencias Biomédicas; Universidad Autónoma de Sinaloa; Sinaloa 80010; México Granados Julio; División de Inmunogenética; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; D.F.; 140...; |
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| Abstract: | AIM: To determine the possible association of the ApoB100 (Xba Ⅰ ), ApoE (Hha Ⅰ ) and CYP7A1 (Bsa Ⅰ ) gene polymorphisms, with the development of cholesterol gallstone disease (GD) in a Mexican population. METHODS: The polymorphisms were analyzed by polymerase chain reaction followed by restriction fragment length polymorphism, in two groups matched by ethnicity, age and sex: patients with GD (n = 101) and stone-free control subjects (n = 101). RESULTS: Allelic frequencies in patients and controls were: 34.... |
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| Keywords: | Apolipoprotein CYP7A1 Gallstones Mexicans Polymorphisms |
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