Mucin phenotype of gastric cancer and clinicopathology of gastric-type differentiated adenocarcinoma |
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Authors: | Tsutomu Namikawa and Kazuhiro Hanazaki |
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Affiliation: | Tsutomu Namikawa, Kazuhiro Hanazaki, Department of Surgery, Kochi Medical School, Kohasu-Okocho, Nankoku-City, Kochi 783-8505, Japan |
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Abstract: | Differentiated adenocarcinoma of the stomach is classified into gastric or intestinal phenotypes based on mucus expression. Recent advances in mucin histochemistry and immunohistochemistry have highlighted the importance of such a distinction, and it is important clinically to distinguish between gastricand intestinal-type differentiated adenocarcinoma. However, a clinical and pathological diagnosis of this type is often difficult in early gastric cancer because of histological similarities between a hyperp... |
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Keywords: | Differentiated adenocarcinoma Gastric cancer Gastric phenotype Mucin core protein Mucous phenotype |
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