| Noradrenergic mechanism in the regulation of seizures in GEPR. |
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| 作者姓名： | Kwang-HoKo Dong-OokSeo Jae-RyunRyu Chan-YoungShin |
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| 作者单位： | DepartmentofPharmacology,CollegeofPharmacy,SeoulNationalUniversity,Seoul,Korea |
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| 摘 要： | Genetically epilepsy prone rat (GEPR) is a model of generalized tonic/clonic epilepsy and a useful tool in the understanding of basic mechanisms of human epilepsy. GEPR is susceptible to audiogenic seizure, hyperthermia induced seizure,and has lower threshold for electrical and chemical stimuli. Several strains of GEPR, from GEPR-3 to GEPR-9, are available depending on the degree of the intensity of audiogenic seizure.
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| 关 键 词： | 去甲肾上腺素 遗传性癫痫 大鼠 动物模型 |
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