| 脑血栓形成患者急性期和恢复期血小板α颗粒膜蛋白-140的变化 |
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| 引用本文： | 赵东红,周玥,王运良,王芹. 脑血栓形成患者急性期和恢复期血小板α颗粒膜蛋白-140的变化[J]. 南方医科大学学报, 2001, 21(4): 303 |
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| 作者姓名： | 赵东红 周玥 王运良 王芹 |
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| 作者单位： | 1. 第一军医大学学员第一旅八队,
2. 解放军148医院, |
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| 摘 要： | 目的研究血小板α颗粒膜蛋白－１４０（ＧＭＰ－１４０）在脑血栓形成患者急性期和恢复期的变化。方法测定５０例 （其中３０例急性期患者，２０例恢复期患者）脑血栓形成患者血浆ＧＭＰ－１４０的含量，并分别与２６名健康人作比较。结果 脑血栓形成患者急性期ＧＭＰ－１４０浓度明显高于恢复期和正常对照组（Ｐ＜０．０１），恢复期与正常对照组间比较差异无显 著性（Ｐ＞０．０５）。结论脑血栓形成患者急性期血浆ＧＭＰ－１４０含量处于较高水平。
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| 关 键 词： | 脑血栓形成 血小板 血小板α颗粒膜蛋白-140(GMP-140) |
| 文章编号： | 1000-2588(2001)04-0303-01 |
| 修稿时间： | 2000-11-27 |
Changes of plasma platelet granule membrane protein-140 in acute and recovery phases of cerebral thrombosis |
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| ZHAO Dong-hong,ZHOU Yue,WANG Yun-liang,WANG Qin. Changes of plasma platelet granule membrane protein-140 in acute and recovery phases of cerebral thrombosis[J]. Journal of Southern Medical University, 2001, 21(4): 303 |
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| Authors: | ZHAO Dong-hong ZHOU Yue WANG Yun-liang WANG Qin |
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| Abstract: | Objective To study the changes of plasma platelet granule membrane protein-140 (GMP-140) in patients with cerebral thrombosis in acute and recovery phases. Methods Fifty patients with cerebral thrombosis in acute phase (n=30, within 7 d from the onset) and recovery phase (n=20, over 30 d from the onset), along with 26 normal subjects, were enrolled in this study. The plasma GMP-140 levels in all the subjects were determined and comparatively analyzed between the groups. Results The average plasma GMP-140 levels in the patients in acute phase were apparently higher than those in patients in recovery phase (P<0.01), while the comparison between the latter and the control group did not reveal significant difference (P>0.05). Conclusion High levels of plasma GMP-140 are present in patients with cerebral thrombosis in acute phase. |
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| Keywords: | cerebral thrombosis platelet platelet granule memjbrane protein-140 |
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