超声测量胎儿侧脑室轻度增宽与临床预后的相关性分析

目的探讨胎儿轻度侧脑室增宽与临床预后之间的关系。方法选择产前检查后发现的胎儿侧脑室后角轻度增宽34例作为观察组,胎儿正常的30例作为对照组,进行新生儿神经行为测定(NBNA)评分,两组比较分析。结果34例胎儿侧脑室轻度增宽中33例做了染色体检查,仅1例染色体为21-三体,1例未查染色体;有3例在妊娠中期被首次发现后因加重而引产;与胎儿性别无统计学意义;观察组的出生后新生儿NBNA评分较对照组高,有统计学意义。结论侧脑室轻度增宽的胎儿,尤其是>12mm的胎儿,出生后发生神经系统发育不良的风险较正常者增加;侧脑室轻度增宽与胎儿性别无关;因胎儿脑室扩张是一动态的过程,如不合并染色体和其他的结构异常,大部分预后良好。

The analysis about mild fetal lateral ventricle and widening of the clinical prognosis

The objective is to investigate the relationship between Mild fetal lateral ventricles and widening of the clinical prognosis.Methods: Of prenatal examination revealed mild posterior horn of the fetal lateral ventricle widened as the study group 34 cases,30 cases of normal fetuses as a control group,neonatal neurobehavioral NBNA score of the two groups.Results: Of 34 cases of fetal lateral ventricle in only 1 case with mild widening of chromosome 21-trisomy,1 case not examined chromosome;3 cases were first discovered in the mid-term pregnancy after induction of labor because of exacerbation;with no significant sex;observation group NBNA newborn after birth rate than the control group,were statistically significant.Conclusion: Slight broadening of the fetal lateral ventricle,especially >12mm fetus,after birth the risk of poor neural development in higher than normal;lateral widening and mild sex of the fetus;because of fetal ventricular expansion is a dynamic process,if not combined with other structural chromosome abnormalities,most of the good prognosis.