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Cutaneous melioidosis with unusual histological features
Authors:B. Yeo  J. Lee  U. Alagappan  J. Y. Pan
Affiliation:National Skin Centre, Singapore
Abstract:Melioidosis is caused by the saprophytic gram‐negative bacillus Burkholderia pseudomallei, and has varied presentations, with cutaneous manifestations occurring in about 13% of cases. The usual histopathological features of melioidosis are suppurative to chronic granulomatous inflammation. Recommended treatment of melioidosis is sequential use of intravenous followed by oral antibiotics for a few months, although oral antibiotics alone can be used in primary cutaneous melioidosis. We report a case of cutaneous melioidosis in a healthy young man, with the unusual histopathological feature of lymphoplasmacytic inflammation, and failing an initial trial of oral antibiotics alone.
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