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Hemophagocytic syndrome and acute liver failure associated with ethylene glycol ingestion: a case report
Authors:Kuskonmaz Baris  Duzova Ali  Kanbur Nuray Oksuz  Gurakan Figen  Gumruk Fatma  Gurgey Aytemiz
Institution:  a Department of Pediatrics, Division of Pediatric Hematology, Hacettepe University Faculty of Medicine, Ankara, Turkey b Department of Pediatrics, Division of Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey c Department of Pediatrics, Division of Adolescent Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey
Abstract:The authors describe a case of accidental ethylene glycol poisoning in an 18-month-old boy who developed hemophagocytic syndrome (HPS). Ethylene glycol is a common substance in various antifreeze preparations. Acute ethylene glycol intoxication is a medical emergency that, if not diagnosed correctly and treated aggressively, will lead to serious neurological, cardiopulmonary, and renal dysfunction, and may result in death. The taking of a detailed history, physical examination, and laboratory testing are essential for diagnosis. To the best of the authors' knowledge this is the first case in the literature of a subject who developed HPS after ethylene glycol intoxication.
Keywords:acute liver failure  ethylene glycol  hemophagocytic syndrome
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