| 一氧化氮与2型糖尿病关系的初步研究 |
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| 引用本文： | 章立,李新荣,徐蘅.一氧化氮与2型糖尿病关系的初步研究[J].东南大学学报(医学版),2000,19(1):23-24. |
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| 作者姓名： | 章立 李新荣 徐蘅 |
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| 作者单位： | 南京铁道医学院,生物化学教研室,江苏,南京,210009 |
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| 基金项目： | 铁道部科技基金资助项目!(J97Z010) |
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| 摘 要： | 目的 :观察 2型糖尿病患者体内一氧化氮 (NO)的改变 ,为从信号传导角度解释 2型糖尿病的发病机制提供新的思路。方法 :以硝酸还原酶法测定 2型糖尿病患者及正常人淋巴细胞内NO水平。结果 :2型糖尿病患者淋巴细胞内NO水平显著下降。结论 :2型糖尿病的发病机制在NO的作用方面与 1型糖尿病比可能有较大差别。
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| 关 键 词： | 一氧化氮 2型糖尿病 淋巴细胞 信号传导 |
Preliminary Study on Relationship between Type 2 Diabetes Mellitus and Nitric Oxide |
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| ZHANG Li,LI Xin-rong,XU Heng.Preliminary Study on Relationship between Type 2 Diabetes Mellitus and Nitric Oxide[J].Journal of Southeast Univ: Medical Sci Ed,2000,19(1):23-24. |
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| Authors: | ZHANG Li LI Xin-rong XU Heng |
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| Abstract: | Objective The purpose of the study was to explain the mechanism of type 2 diabetes mellitus in respect of signal transduction,through observing the changes in level of nitric oxides.Methods Determining the level of NO in lymphocyte of type 2 diabetes mellitus patients and healthy people with the method of nitrate reductase.Result The concentration of NO was greatly descended compared with that of healthy people.Conclusion The effect of NO on the mechanism of type 2 diabetes mellitus was considerabley different from that on the mechanism of type 1 diabetes mellitus. |
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| Keywords: | nitric oxide type 2 diabetes mellitus lymphocytes signal transduction |
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