老年患者原发性肝细胞癌肝切除术后疗效分析

目的 探讨老年原发性肝细胞癌患者行肝切除术后的治疗效果.方法 自1989年1月至2008年12月,共有1 225例原发性肝细胞癌患者于我院行肝切除术,挑选其中年龄≥60岁、有完整临床资料及随访结果的112例患者进行回顾性分析,并随机抽取同期年龄＜60岁的135例患者作对照.结果 老年组患者术后并发症发生率为8.9%(1...

Outcomes of elderly patients with hepatocelluar carcinoma undergone hepatectomy

Objective To evaluate the curative effect of hepatectomy for elderly patients with hepatocelluar carcinoma(HCC).Methods From January 1989 to December 2008,1 225 patients with HCC underwent hepatectomy in our hospital.The clinical data and treatment outcomes of 112 elderly patients suffered from HCC(elderly group,≥60 years of age) and 135 younger patients(control group,<60 years of age) who selected randomly from the 1 225 patients were retrospectively analyzed.Results The rate of postoperative complications was 8.9%(10/112) in the elderly group,and 11.1%(15/135) in the control group.There was no significant difference between two groups.The tumor-free survival rates after hepatectomy at 1,3 and 5 years were 66.2%,48.7% and 43.2% in the elderly group respectively,and 63.2%,41.2% and 37.3% in the control group,respectively.The was no significant difference between two groups.The overall survival rates after hepatectomy at 1,3 and 5 year were 82.2%,55.4% and 43.5% in the elderly group respectively,and 70.8%,37.1% and 30.9% in the control group,respectively.The postoperative long-term survival rate in the elderly group was significantly better than that in the control group(P=0.012).Conclusion Hepatic resection is effective for elderly patients with HCC.For the elderly patients without preoperative comorbidities or with controlled comorbidities,hepatic resection is a safe and effective treatment.