电针对狗血浆部分脑肠肽含量的影响及意义

为观察电针对狗血浆中部分脑肠肽（BGP）含量的影响，以初步探讨电针调控胃功能的作用机制，将20条狗随机分为4组（空白对照组，非经非穴组，上巨虚组，足三里组），每组5条，采用放免分析法监测电针不同穴位针刺前后狗血浆中胃泌素（GT），血管活性肠肽（VIP），生长抑素（SS）及内皮素（ET）含量的变化。结果显示，电针足三里穴后血浆中GT，VIP含量上升（P＜0．05），SS，ET含量下降（P＜0．05）；电针上巨虚穴后血浆中ET含量下降（P＜0．05），但下降趋势不知足三里组明显，而GT，VIP，SS含量无显著变化；其他组各监测指标无显著变化；结果提示，电针可影响狗血浆中脑肠肽的含量，并可能通过这种影响来调整胃功能，具有一定的经络和穴位特异性。

EFFECTS OF ELECTROACUPUNCTURE ON PLASMA LEVELS OF BRAIN-GUT PEPTIDES IN DOGS

To observe the regulative effect of electroacupuncture(EA) on plasma levels of some brain gut peptides in dogs, contents of gastric secretin(GT), vasoactive intestinal peptide(VIP), somatostatin(SS) and endothelin(ET) in plasma were simultaneously measured by radioactive immunonassay method in the dogs with or without EA stimulation at different acupoints. The results showed that in the Zusanli(st 36) group, after EA stimulation, an increase was observed in plasma contents of GT and VIP( P <0 05) whereas a decrease was found in plasma contents of SS and ET ( P <0 05) as compared with those of the control group. In the Shangjuxu(st 37) group, after EA stimulation, a decrease in plasma content of ET( P <0 05) was observed, but the change was not as significant as that in the Zusanli group. No significant changes were observed in other groups.The conclusion is electroacupuncture can significantly change the levels of some brain gut peptides in plasma of dogs and it is acupoint specific.