老年高血压病患者血压变异性对血小板体积、高敏C反应蛋白的影响 |
| |
引用本文: | 杜江川,赵洛沙,李阳,张化勇,胡广云,魏经汉.老年高血压病患者血压变异性对血小板体积、高敏C反应蛋白的影响[J].中国循证心血管医学杂志,2011,3(5):359-361. |
| |
作者姓名: | 杜江川 赵洛沙 李阳 张化勇 胡广云 魏经汉 |
| |
作者单位: | 郑州大学第一附属医院心内科,450052 |
| |
摘 要: | 目的探讨老年高血压病患者血压变异性(BPV)对平均血小板体积(MPV)及高敏C反应蛋白(hsCRP)的影响。方法入选初诊的老年高血压病患者120例,行24h动态血压监测(ABPM),根据24h收缩压标准差(SSD)第50百分位数(P50),分为高BPV组和低BPV组,每组60例。另入选血压正常的40例老年健康者作为对照组。检测各组患者BPV、MPV及hsCRP水平,并进行比较分析。结果与对照组相比,高血压病患者BPV值显著增加(P〈0.05)。高血压病患者MPV、hsCRP水平与对照组(P〈0.05),高BPV组MPV、hsCRP水平与低BPV组(P〈0.05)间的差异均有显著统计学意义。MPV值、hsCRP值与SSD的呈正相关(r分别为0.592、0.795,P〈0.05)。结论老年高血压病患者的血压变异对MPV、hsCRP显著影响,可促进血小板活化及炎症反应。
|
关 键 词: | 高血压 血压变异性 血小板活性 高敏C反应蛋白 |
Influences of blood pressure variability on platelet volume and high-sensitivity C-reactive protein in senile hypertensive patients |
| |
Authors: | DU Jiang-chuan ZHAO Luo-sha LI Yang ZHANG Hua-yong HU Guang-yun WEI Jing-han |
| |
Institution: | DU Jiang-chuan,ZHAO Luo-sha,LI Yang,ZHANG Hua-yong,HU Guang-yun,WEI Jing-han.Department of Cardiology,First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China. |
| |
Abstract: | Objective To discuss the influences of blood pressure variability(BPV) on mean platelet volume(MPV) and high-sensitivity C-reactive protein(hsCRP) in senile hypertensive patients.Methods The senile hypertensive patients with tentative diagnosis were selected(n=120) and given 24-hour ambulatory blood pressure monitoring(ABPM).All patients were divided into high BPV group and low BPV group(each n=60) according to the 50th percentile(P50) of 24-hour systolic pressure standard deviation(SSD).Other senile health... |
| |
Keywords: | Hypertension Blood pressure variability Platelet activity High-sensitivity C-reactive protein |
本文献已被 CNKI 维普 万方数据 等数据库收录! |
|