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老年高血压病患者血压变异性对血小板体积、高敏C反应蛋白的影响
引用本文:杜江川,赵洛沙,李阳,张化勇,胡广云,魏经汉.老年高血压病患者血压变异性对血小板体积、高敏C反应蛋白的影响[J].中国循证心血管医学杂志,2011,3(5):359-361.
作者姓名:杜江川  赵洛沙  李阳  张化勇  胡广云  魏经汉
作者单位:郑州大学第一附属医院心内科,450052
摘    要:目的探讨老年高血压病患者血压变异性(BPV)对平均血小板体积(MPV)及高敏C反应蛋白(hsCRP)的影响。方法入选初诊的老年高血压病患者120例,行24h动态血压监测(ABPM),根据24h收缩压标准差(SSD)第50百分位数(P50),分为高BPV组和低BPV组,每组60例。另入选血压正常的40例老年健康者作为对照组。检测各组患者BPV、MPV及hsCRP水平,并进行比较分析。结果与对照组相比,高血压病患者BPV值显著增加(P〈0.05)。高血压病患者MPV、hsCRP水平与对照组(P〈0.05),高BPV组MPV、hsCRP水平与低BPV组(P〈0.05)间的差异均有显著统计学意义。MPV值、hsCRP值与SSD的呈正相关(r分别为0.592、0.795,P〈0.05)。结论老年高血压病患者的血压变异对MPV、hsCRP显著影响,可促进血小板活化及炎症反应。

关 键 词:高血压  血压变异性  血小板活性  高敏C反应蛋白

Influences of blood pressure variability on platelet volume and high-sensitivity C-reactive protein in senile hypertensive patients
Authors:DU Jiang-chuan  ZHAO Luo-sha  LI Yang  ZHANG Hua-yong  HU Guang-yun  WEI Jing-han
Institution:DU Jiang-chuan,ZHAO Luo-sha,LI Yang,ZHANG Hua-yong,HU Guang-yun,WEI Jing-han.Department of Cardiology,First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China.
Abstract:Objective To discuss the influences of blood pressure variability(BPV) on mean platelet volume(MPV) and high-sensitivity C-reactive protein(hsCRP) in senile hypertensive patients.Methods The senile hypertensive patients with tentative diagnosis were selected(n=120) and given 24-hour ambulatory blood pressure monitoring(ABPM).All patients were divided into high BPV group and low BPV group(each n=60) according to the 50th percentile(P50) of 24-hour systolic pressure standard deviation(SSD).Other senile health...
Keywords:Hypertension  Blood pressure variability  Platelet activity  High-sensitivity C-reactive protein  
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