| 保留肾上腺手术治疗醛固酮瘤的可行性 |
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| 引用本文： | 刘宇军,张立,孙立安,林宗明,朱同玉,许明,张永康,王国民.保留肾上腺手术治疗醛固酮瘤的可行性[J].中国临床医学,2009,16(4):590-591. |
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| 作者姓名： | 刘宇军 张立 孙立安 林宗明 朱同玉 许明 张永康 王国民 |
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| 作者单位： | 复旦大学附属中山医院泌尿外科,上海,200032 |
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| 摘 要： | 目的：分析保留肾上腺组织的手术（ASS）治疗醛固酮瘤的可行性。方法：醛固酮瘤（APA）85例，行患侧肾上腺全切65例，ASS20例。随访5～60个月，平均21．2个月，比较两种手术方法的疗效。结果：患侧肾上腺全切组治愈率、缓解率、失败率分别为72．3％（47／65），23．1％（15／65），4．6％（3／65）；ASS组分别为80．0％（16／20），5．0％（1／20），15．0％（3／20），两组无显著差异（P〉0．05）。患侧全切组术后血钾全部正常，3例高血压不改善者，高血压病程达14～30年，同时合并动脉硬化或肾功能不全；3例ASS治疗失败者，术后持续或复发低血钾和高血压，CT及再次手术病理证实为一侧多发腺瘤。8．2％（7／85）的患者肿瘤为多灶性。结论：单发性APA适合于ASS手术，肿瘤多灶性是造成ASS治疗失败的重要原因。ASS失败的患者，再次行患侧肾上腺切除或肿瘤切除可获得良好疗效。
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| 关 键 词： | 原发性醛固酮增多症 醛固酮瘤 肾上腺切除 |
Adrenal-sparing Surgery in Patients with Aldosterone-Producing Adenomas |
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| LIU Yujun,ZHANG Li,SUN Lian,LIN Zongming,ZHU Tongyu,XU Ming,ZHANG Yongkang,WANG Guomin.Adrenal-sparing Surgery in Patients with Aldosterone-Producing Adenomas[J].Chinese Journal Of Clinical Medicine,2009,16(4):590-591. |
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| Authors: | LIU Yujun ZHANG Li SUN Lian LIN Zongming ZHU Tongyu XU Ming ZHANG Yongkang WANG Guomin |
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| Institution: | LIU Yujun ZHANG Li SUN Lian LIN Zongming ZHU Tongyu XU Ming ZHANG Yongkang WANG Guomin Department of Urology,Zhongshan Hospital,Fudan University,Shanghai 200032,China |
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| Abstract: | Objective:To compare the results of adrenal-sparing surgery (ASS) and unilateral total adrenalectomy in patients with aldosterone-producing adenomas (APA),and to analyze the feasibility of ASS. Methods:A total of 85 cases of APA were treated by surgery from Jan.2004 to Dec.2008. Total unilateral adrenalectomy were performed in in 65 cases and ASS were performed in 20. At a mean follow-up of 21.2 (range,5 to 60) months,the results were reviewed retrospectively,and the outcome were categorized based on postop... |
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| Keywords: | Primary aldosteronism Aldosterone-producing adenomas Adrenalectomy |
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