乳酸菌素片治疗功能性消化不良效果观察

目的:评价乳酸菌素片治疗功能性消化不良(FD)的效果.方法:将63例FD患者随机分组,治疗组35例,在给予胃肠动力及抑酸剂等综合治疗的基础上加用乳酸菌素片4～5片,4～5小时嚼服1次,连续用药15天;对照组28例,仅给予综合治疗,连续15天.观察两组自觉症状改善程度.结果:治疗组显效12例(34.3%),有效20例(57.1%),总有效率91.4%;对照组显效4例(14.3%),有效13例(46.4%),总有效率60.7%.治疗组疗效明显高于对照组(P＜0.01)).结论:改善肠道内环境及调整肠道菌群也是治疗FD的方法之一.

Efficacy of Lacidophilin Tablets in Treatment of Functional Dyspepsia

Objective:To evaluate the efficacy of Lacidophilin tablets in treatment of functional dyspepsia(FD).Methods:Totally,63 cases of FD were randomly divided to two groups.The treatment group(n=35),in addition to routine therapy,was given orally 4~5 tablets of Lacidophilin tablets a time,4 times a day for 15 days,while the matched control group(n=28) was given routine therapy,the efficacy of the treatment was observed and compared between the two groups.Results:Excellent response was obtained in 12 cases of the treatment group(34.3%);response in another 20 cases(57.1%);the overall effective rate in the treatment group was 91.4%.Whereas,excellent response was found only in 4 cases of the control group;response in 13 cases;the overall response rate was 60.7%.There was a significant difference between the two groups(P<0.01).Conclusions:Improvement of intestinal tract environment and adjustment of its microbial population were shown to be one of the therapies of FD.