外阴尖锐湿疣的免疫组织化学研究

采用免疫组化链霉菌素抗生物素蛋白—过氧化物酶连接法（ＳＰ法），对病理学上诊断或拟诊为尖锐湿疣的９６例外阴活检标本进行人乳头状瘤病毒（ＨＰＶ）抗原检测。结果表明尖锐湿疣ＨＰＶ的阳性率为５９．３８％，ＳＰ法对可疑病例，可作为病原学诊断的依据。对组织学形态不够典型的病例和尚未形成诊断性挖空细胞的早期病例，具有重要的辅助诊断价值。

Immunohistochemical Study on Human Papillomavirus Infection of the Vulva/

Ninety six cases of human papillomavirus infection of the vulva from March 1993 to October 1996 in the Affiliated Hospital of Guilin Medical College were immunohistochemically studied by SP method to detect HPV Ag The results showed that the presence of diagnostic koilocytes was very important in diagnosis of HPV infection in routine pathological examination, but in cases of atypical morphological changes, especially diagnostic koilocytes were not formed in early stage, the demonstration of browm color granules in the nuclei of prickle cells by immunohistochemical method was of diagnostic value for condylomata acuminata. The pathological diagnosis and the way of spread of condylomata acuminata are disccussed.