| 复方补乌糖浆质量标准研究 |
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| 引用本文： | 高家荣,程志清,夏伦祝. 复方补乌糖浆质量标准研究[J]. 中国药房, 2009, 0(24): 1890-1892 |
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| 作者姓名： | 高家荣 程志清 夏伦祝 |
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| 作者单位： | 安徽中医学院第一附属医院药学部,合肥市230031 |
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| 摘 要： | 目的:建立复方补乌糖浆的质量标准。方法:采用薄层色谱(TLC)法对制剂中补骨脂、当归、川芎、丹参进行定性鉴别;采用高效液相色谱法测定方中补骨脂素和异补骨脂素的含量。结果:补骨脂、当归、川芎、丹参的TLC斑点清晰、分离度好。补骨脂素和异补骨脂素的进样量分别在0.030 4~0.304μg(r=0.999 1)和0.036 2~0.362μg(r=0.999 5)范围内与其峰面积积分值呈良好线性关系;二者平均回收率分别为100.1%和102.4%,RSD分别为2.9%和2.7%。结论:所建标准可用于复方补乌糖浆的质量控制。
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| 关 键 词： | 复方补乌糖浆 薄层色谱法 高效液相色谱法 补骨脂素 异补骨脂素 质量标准 |
Quality Standard of Compound Buwu Syrup |
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| GAO Jia-rong,CHENG Zhi-qing,XIA Lun-zhu. Quality Standard of Compound Buwu Syrup[J]. China Pharmacy, 2009, 0(24): 1890-1892 |
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| Authors: | GAO Jia-rong CHENG Zhi-qing XIA Lun-zhu |
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| Affiliation: | (The First Affiliated Hospital of Anhui College of TCM, Hefei 230031, China) |
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| Abstract: | OBJECTIVE： To establish the quality standard of Compound buwu syrup. METHODS： TLC was employed to identify Psoralea corylifolia , Angelica sinensis, Ligusticum chuanxiong and Salvia miltiorrhiza .HPLC was applied for the determination of the contents of psoralen and isopsoralen. RUSULTS： Psoralea corylifolia, Angelica sinensis, Ligusticurn chuanxiong and Salvia miltiorrhiza were all well- separated with clear TLC spots. The linear ranges of psoralen and isopsoralen were 0.030 4--0.304 μg（r = 0.999 1） and 0.036 2--0.362 μg（r = 0.999 5）, respectively and the average recoveries were 100.1% （RSD = 2.9% ） and 102.4% （RSD = 2.7% ）, respectively. CONCLUSION ： The established standard is applicable for the quality control of Compound buwu syrup. |
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| Keywords: | Compound huwu syrup TLC HPLC Psoralen Isopsoralen Quality standard |
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