| 生姜抗晕动病有效部位化学成分分析 |
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| 引用本文： | 宣伟东,卞俊,刘娟,王朝武,袁兵. 生姜抗晕动病有效部位化学成分分析[J]. 中国药房, 2009, 0(30): 2362-2364 |
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| 作者姓名： | 宣伟东 卞俊 刘娟 王朝武 袁兵 |
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| 作者单位： | 解放军第411医院南京军区药学专科中心,上海市200434 |
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| 摘 要： | 目的:分析生姜抗晕动病有效部位的化学成分。方法:用正己烷提取有效部位,采用气相色谱-质谱联用(GC-MS)法分析提取物中化学成分;采用高效液相色谱(HPLC)法测定提取物中抗晕活性成分6-姜酚的含量。结果:GC-MS法测定提取物中烯类占61.41%,姜酚类占21.60%,姜酮类占4.90%,醇类占2.74%,含量较高的为姜烯(23.596%)和6-姜酚(15.004%);HPLC法测定提取物中6-姜酚的含量为15.97%。结论:生姜抗晕动病有效部位中烯类和姜酚类成分含量较高。HPLC法可作为生姜抗晕动病有效部位6-姜酚的质控方法。
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| 关 键 词： | 生姜 6-姜酚 晕动病 气相色谱-质谱联用法 高效液相色谱法 |
Analysis of Chemical Compositions of the Effective Anti - kinesia Fraction from Zingiber officinale |
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| XUAN Wei-dong,BIAN Jun,LIU Juan,WANG Chao-wu,YUAN Bing. Analysis of Chemical Compositions of the Effective Anti - kinesia Fraction from Zingiber officinale[J]. China Pharmacy, 2009, 0(30): 2362-2364 |
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| Authors: | XUAN Wei-dong BIAN Jun LIU Juan WANG Chao-wu YUAN Bing |
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| Affiliation: | (Nanjing Military Command Pharmaceutics Center,No. 411 Hospital of PLA, Shanghai 200434, China) |
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| Abstract: | OBJECTIVE ： To analyze the chemical compositions of the effective anti - kinesia fraction of Zingiber officinale .METHODS： The effective fraction was extracted by using n-hexane, and the chemical compositions of the extract were analyzed by GC-MS. The content of 6- gingerol in n-hexane extract was determined by HPLC. RESULTS： The constituents of effective fraction were composed of alkenes（61.41% ）, gingerols（21.60% ）, gingerones（4.90 % ） and alcohols （2.74%）, with Zingiberene（23. 596% ） and 6-gingerol（ 15.004% ） taking the lead in terms of content. The content of 6-gingerol which determined by HPLC was 15.97%. CONCLUSION： The contents of alkenes and gingerols are high in the effective anti- kinesia fraction of Z.officinale .HPLC can be used as a quality control method for the 6-gingerol in the effective anti- kinesia fraction of Z.officinale. |
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| Keywords: | Zingiber officinale 6-Gingerol Kinesia GC-MS HPLC |
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