球后注射曲安奈德联合激光光凝治疗糖尿病弥漫性黄斑水肿的临床观察

目的观察球后注射曲安奈德(TA)联合激光光凝治疗糖尿病性弥漫性黄斑水肿的疗效。方法34例48眼经眼底检查、荧光素眼底血管造影(FFA)检查确诊的糖尿病性弥漫性黄斑水肿患者24眼球后注射TA联合激光光凝,24眼单纯激光光凝,随访6m,观察治疗前后患眼视力、眼底情况、眼压以及眼底荧光素血管造影的变化。结果联合组视力提高15眼(62.5%),视力不变5眼(20.8%),视力下降4眼(16.7%)。水肿减轻20眼(83.3%),水肿未退4眼(16.7%)。单纯光凝组视力提高5眼(20.8%),视力不变12眼(50%),视力下降7眼(29.2%)。水肿减轻9眼(37.5%),水肿未退15眼(62.5%)。结论光凝治疗糖尿病弥漫性黄斑水肿时联合球后注射曲安奈德球可促进水肿吸收和视力改善,且安全、方便。

Retrobulbar injection triamcinolone acetonide (TA)combined laser photocoagulation treatment on diffused diabetic macular edema

Objective To investigate the effect of retrobulbar injection of triamcinolone acetonide (TA) combined with laser photocoagulation treatment on diffused diabetic macular edema. Methods Thirty- four patients (48 eyes)with diffused diabetic macular edema diagnosed by ocular-fundus examination, fundus fluorescein angiography ( FFA) ,Twenty-four eyes of them were treated with retrobulbar injection triamcino lone acetonide (TA) combined laser photocoagulation and 24 eyes only laser photocoagulation. The follow-up time was 1, 3, and 6 months. Visual acuity and fundus fluorescein an-giography were measured. Results Among patients with retrobulbar injection triamcinolone acetonide (TA) combined laser photocoagulation ,visual acuity in 15 eyes (62.5%) was improved in 2 lines or more and 5 eyes(20.8%) remained no change, edema in 20 eyes (83.3%) reduced after treament. Among patients with laser photocoagulation ,visual acuity in 5 eyes (20.8%) was improved in 2 lines or more and 12 eyes (50%) remained no change, edema in 9 eyes(37.5%) reduced after treatment. Conclusions The result of retrobulbar injection triamcinolone acetonide (TA) combined Laser photocoagulation treatment for diffused diabetic macular edemae is better than those of only using laser photocoagulation.