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From skin dendritic cells to a simplified classification of human and mouse dendritic cell subsets
Authors:Martin Guilliams  Sandrine Henri  Samira Tamoutounour  Laurence Ardouin  Isabelle Schwartz‐Cornil  Marc Dalod  Bernard Malissen
Affiliation:1. Centre d'Immunologie de Marseille‐Luminy, Université de la Méditerranée, Marseille Cedex 9, France;2. INSERM, U631, Marseille Cedex 9, France;3. CNRS, UMR6102, Marseille Cedex 9, France;4. Virologie et Immunologie Moléculaires, UR892 INRA, Jouy‐en‐Josas, France
Abstract:Recent studies have identified several DC subsets within the mouse skin and showed that functional specialization exists among them. This Viewpoint summarizes recent data on functional specialization of skin DC subsets and integrates this knowledge into a unifying DC classification that emphasizes the similarities between the DC subsets found in both lymphoid and nonlymphoid tissues of several mammalian species.
Keywords:DC  Human  Mouse  Skin  Subsets
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