| 老年慢性肺心病脂质过氧化研究 |
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| 引用本文： | 刘韵蝉,梅元英,唐筑灵. 老年慢性肺心病脂质过氧化研究[J]. 中国民康医学, 2001, 13(4): 211-212 |
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| 作者姓名： | 刘韵蝉 梅元英 唐筑灵 |
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| 作者单位： | 1. 550001,贵阳医学院附属医院
2. 贵州省老年医学研究所 |
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| 摘 要： | 目的研究老年慢性肺心病患者脂质过氧化损伤与病情演变的关系及其衰老的影响.方法采用硫代巴比妥酸比色法测定血清过氧化脂质(LPO),放射免疫法测定超氧化物歧化酶(SOD).结果三组病人上述指标差异有显著性(P＜0.01),肺心病急性发作期又高于肺心病缓解期(P＜0.05),结论老年肺心病患者存在脂质过氧化反应的增强,在肺心病病情变化的不同时期,氧自由基(OFR)对肺组织的损伤与病情密切相关,机体的衰老加重这一过程.
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| 关 键 词： | 肺心病 氧自由基 过氧化脂质 超氧化物歧化酶 |
| 修稿时间： | 2001-01-02 |
A study on lipide peroxide of aged chronic pulmonary heart disease. |
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| LIU Yunchan,MEI Yuanying,TANG Zhuling. A study on lipide peroxide of aged chronic pulmonary heart disease.[J]. medical journal of chinese peoples health, 2001, 13(4): 211-212 |
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| Authors: | LIU Yunchan MEI Yuanying TANG Zhuling |
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| Affiliation: | LIU Yunchan,MEI Yuanying,TANG Zhuling.The Affiliated Hospital of Guiyan Medical University,550000,China |
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| Abstract: | Objectives:To study damage,development and senile on lipide peroxide of aged chronic pulmonary heart disease.Methods:Measuring LPO by thiobarbituric acid colorimetric measure and measuring SOD by radio|immunity measure.Results:LPO and SOD had significant difference among three groups of patients ( P< 0 01).LPO and SOD of pulmonary heart disease in acute stage were higher than that of remission stage( P< 0 05).Conclusion:Lipide peroxide reaction of aged pulmonary heart disease patients was serious and damage level of lung that was caused by OFR was correlated with stage of the illness.The old and feeble made the disease worese. |
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| Keywords: | Aged pulmonary heart disease OFR LPO SOD |
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