急性冠脉综合征患者血尿酸升高相关因素分析

目的:探讨急性冠脉综合征(ACS)患者血尿酸升高的相关因素。方法:将ACS患者78例按照血尿酸水平分为A组(血尿酸<350μmmol/L)46例、B组(血尿酸≥350μmmol/L)32例,并在门诊体检人群中选取未患急性冠脉综合征的高尿酸志愿者(血尿酸≥350μmmol/L)30例作为C组,记录各组病例的年龄、性别、吸烟史、高血压史、糖尿病史、左室射血分数(LVEF)、血肌酐(Cr)、血尿素氮(BUN)、甘油三酯(TG)、总胆固醇(CHO)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、空腹血糖等指标。结果:A、B两组吸烟史、Cr、BUN、TG、LVEF、CHO、HDL、LDL存在显著差异(P<0.05);B、C两组患者LVEF、CHO、HDL、LDL存在显著差异(P<0.05)。结论:吸烟史以及Cr、BUN、TG水平升高可能是急性冠脉综合征患者血尿酸升高的相关因素。

Correlation between occurrence of acute coronary syndrome and elevated blood uric acid level

Objective: To investigate correlation between occurrence of acute coronary syndrome(ACS) and elevated blood uric acid level.Methods: A total of 78 patients of ACS were divided into group A(46 cases,serum uric acid <350μmmol/L),group B(32 cases,serum uric acid ≥ 350μmmol/L),according to serum uric acid levels.Thirty volunteers with high uric acid volunteers but without acute coronary syndrome(uric acid ≥ 350μmmol / L) were assigned as group C.Parameters including age,sex,smoking history,history of hypertension,diabetes mellitus,left ventricular ejection fraction(LVEF),creatinine(Cr),blood urea nitrogen(BUN),triglyceride(TG),total cholesterol(CHO),high density lipoprotein(HDL),low density lipoprotein(LDL),fasting glucose were recorded and compared among the three groups.Results: There were significant differences in smoking history,and Cr,BUN,TG,LVEF,CHO,HDL,LDL levels between group A and B(P<0.05);group B and C patients showed significant difference in LVEF,CHO,HDL,LDL were significantly different(P<0.05).Conclusions: Smoking history,elevated Cr,BUN,TG levels may correlated with occurrence of acute coronary syndrome.