脾切除对几种血液病的治疗作用(附56例分析)

目的 总结对血液病病人行脾切除的治疗效果、适应证和手术并发症。方法 回顾性分析１９８１～１９９８年间５６例血液病病人脾切除术的资料，根据治疗效果，总结出适应证及并发症的预防。结果 根据血液学参数结果，脾切除对原发性血小板减少性紫癜、遗传性球形红细胞增多症、自身免疫性溶血性贫血、原发性血小板减少性紫癜合并自身免疫性溶血性贫血（Ｅｖａｎｓ病）有确切的治疗效果，有效率分别为８７．５％，８０％，７７．８％

Splenectomy for some hematologic diseases

Objective To investigate the therapeutic efficacy, indications and complications of splenectomy performed in patients suffering from hematological diseases. Methods From 1981 to 1998, 56 patients suffering from hematological diseases underwent splenectomy in our hospital. We summed up the indications, ideal operational opportunity and the ways of preventing the complications. Results Determination of postoperative hematological parameters indicated that splenectomy could exert significant therapeutic effects on the diseases of idiopathic thrombocytopenic purpura (ITP), hereditary spherocytosis (HS), autoimmune hemolytic anemia (AHA) and Evans syndrome. The effective rates were 87.5%, 80.0%, 77.8% and 66.7%, respectively. Conclusions Splenectomy is effective for treatment of some hematological diseases. Reasonable use of hormone does not result in increase postoperative infections. It is unnecessary to use antibiotics for a long time after the operation.