Orexin A Suppresses the Expression of Exosomal PD-L1 in Colon Cancer and Promotes T Cell Activity by Inhibiting JAK2/STAT3 Signaling Pathway |
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Authors: | Wen Jing Chang Xiaocen Bai Bowen Gao Qian Zhao Yuyan |
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Affiliation: | 1.Department of Endocrinology, Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, Liaoning, China ;2.Department of Endocrinology, First Affiliated Hospital of China Medical University, 155 Nanjing North Street, Shenyang, 110001, Liaoning, China ; |
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Abstract: | Digestive Diseases and Sciences - Colon cancer, ranked third in cancer related mortality, is the most common malignant cancer of digestive tract. Though immune checkpoint inhibitors show promising... |
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