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Neuritogenesis of retinal ganglion cells is differentially promoted by target extract
Authors:Alejandra Bosco, N  stor G. Carri,Rafael Linden
Affiliation:Alejandra Bosco, Néstor G. Carri,Rafael Linden
Abstract:Labeled retinal ganglion cells from neonatal rats extended neurites in dissociated cell culture as a cell type-specific response to ihe influence of a superior collicular extract. The molecule responsible for this neuritogenic effect is soluble and non-dialysable (> 12kDa). Nerve growth factor had a neuritogenic effect both on ganglion cells and other types of retinal cells.
Keywords:CNS   Retina   Superior colliculus   NGF   Neurite outgrowth   Rat
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