| 胰激肽释放酶对脑缺血沙土鼠软脑膜微血管血流量的影响 |
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| 引用本文： | 薛全福,王耀芳.胰激肽释放酶对脑缺血沙土鼠软脑膜微血管血流量的影响[J].微循环学杂志,1997,7(1):23-24. |
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| 作者姓名： | 薛全福 王耀芳 |
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| 作者单位： | 中国协和医科大学中国医学科学院基础医学研究所病理生理研究室，江苏省常州生物化学制药厂 |
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| 摘 要： | 胰激肽释放酶对脑缺血沙土鼠软脑膜微血管血流量的影响薛全福１吴云清１张宏１斯勤１王耀芳２蒋建平胰激肽释放酶（ＰａｎｃｒｅａｔｉｃＫａｌｉｋｒｅｉｎ，ＰＫ）是一种蛋白水解酶，在体内作用于激肽原，释放出激肽而发挥作用。在国内外已取得良好的临床效果，并已用于...
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| 关 键 词： | 微循环血流量 软脑膜微血管 胰激肽释放酶 激光多普勒微循环血流计 |
Page 23/Effect of Pancreatic Kallikrein on Pail Microcirculatory Blood Flow in Brain Ischemic Gerbil |
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| Xue Quanfu,Wu Yunqing,Zhang Hong/Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences and China Union of Medical University,Beijing.Page 23/Effect of Pancreatic Kallikrein on Pail Microcirculatory Blood Flow in Brain Ischemic Gerbil[J].Chinese Journal of Microcirculation,1997,7(1):23-24. |
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| Authors: | Xue Quanfu Wu Yunqing Zhang Hong/Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and China Union of Medical University Beijing |
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| Institution: | Xue Quanfu,Wu Yunqing,Zhang Hong/Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences and China Union of Medical University,Beijing 100005 |
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| Abstract: | Pancreatic Kallikrein(70U/mg, 10mg/kg body weight) was injected intraveneously in gerbil and then bilateral caroid arteries were ligated. Pail microcirculatory blood flow was measured by using Laser Doppler flowmeter through parietal cranial window before and after ligation. Results showed that pail microcirculatory blood flow was increased obviously in the Pancreatic Kallikrein administrated gerbil compared with the nontreated gerbil and could reach to 75% of the normal control level. Results proved that Pancreatic Kallikrein could improve the pail microcirculation in brain ischemic gerbil. Which implied this drug could be used in brain ischemic patient. |
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| Keywords: | Microcirculatory blood flow Pail microvessel Pancreatic Kallikrein Laser Doppler flowmeter |
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