| 决明子抗氧化作用的研究 |
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| 引用本文： | 雷嘉川,余建清,廖志雄. 决明子抗氧化作用的研究[J]. 中国中医药信息杂志, 2006, 13(11): 41-42 |
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| 作者姓名： | 雷嘉川 余建清 廖志雄 |
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| 作者单位： | 1. 武汉大学人民医院药学部,湖北,武汉,430060
2. 武汉大学药学院,湖北,武汉,430072 |
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| 摘 要： | 目的研究决明子提取物的抗氧化作用。方法以光照核黄素体系产生超氧阳离子(O2-),测定决明子提取物对O2-的清除能力;以3种自由基生成体系诱导的红细胞膜脂质过氧化为模型,测定决明子提取物对脂质过氧化的抑制作用。结果决明子提取物显示了强的清除O2-能力,对黄嘌呤-黄嘌呤氧化酶系统、过氧化氢(H2O2)及紫外线照射3种方法引起的细胞膜脂质过氧化均有抑制作用,其作用呈剂量依赖性。结论决明子提取物有较好的抗氧化作用。
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| 关 键 词： | 决明子 抗氧化 细胞膜 |
| 文章编号： | 1005-5304（2006）11-0041-02 |
| 收稿时间： | 2006-03-30 |
| 修稿时间： | 2006-03-30 |
Study on Antioxidant Activity of Extract of Cassia Obtusifolia |
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| LEI Jia-chuan,YU Jian-qing,LIAO Zhi-xiong. Study on Antioxidant Activity of Extract of Cassia Obtusifolia[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2006, 13(11): 41-42 |
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| Authors: | LEI Jia-chuan YU Jian-qing LIAO Zhi-xiong |
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| Affiliation: | 1.Renmin Hospital of Wuhan University, Wuhan 430060, China;2.College of Pharmacy, Wuhan University, Wuhan 430072, China |
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| Abstract: | Objective To study antioxidant activity of extract of Cassia obtusifolia. Method The free radical-scavenging effect of the extract was evaluated in the flavins system; erythrocyte membrane was exposed to three radicals generation systems, the inhibition of the extract on lipid peroxidation was determined. Results The extract showed strong scavenging effect on superoxide radical and dose- dependently inhibited the increases of lipid peroxidation content in the membrane exposed to xanthine-xanthine oxidase system, H2O2 or UV light. Conclusion Antioxidant activity of the extract was obvious. |
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| Keywords: | Cassia obtusifolia antioxidant activity erythrocyte membrane |
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