国产Amplatzer封堵器治疗膜周型室间隔缺损疗效观察

目的评价国产Amplatzer封堵器治疗先天性心脏病室间隔缺损（VSD）的临床疗效及其应用前景。方法选择22例VSD患者（男12例,女10例,年龄7-40岁）,其中伴膜部瘤者有1例,VSD直径（3.5-8.9mm）。在经胸超声心动图（TTE）及X线影像指导下,经鞘管应用合适的国产Amplatzer封堵伞进行封堵,术后应用超声心动图观察疗效。结果在对患者1年的随访中,除1例有少量残余分流外,余未见残余分流,瓣膜反流程度无加重。结论应用国产Amplatzer封堵器介入治疗VSD操作简单,成功率高,疗效可靠、安全,近期临床疗效好。

Curative effect of homemade ventricular septal occluder in the treatment of perimembranous ventricular septal defects

ObjectiveTo evaluate the therapeutic effects and clinical future of transcatheter closure of perimembranous ventricular septal defect(VSD) using occluder made in China.MethodsA total of 22 VSD patients,12 males and 10 females,aging from 7 to 40 years,including a patient with ventricular septal aneurysm were enrolled in our study.The diameters of VSD ranged from 3.5 to 8.9 mm.Under the guidance of transthoracic echocardiography(TEE) and X-ray,appropriate ventricular septal occluders were applied to perform transcatheter closure with the filament path.And the successful cases were examined by TEE after operation.ResultsDuring 1 year postoperative follow-up to observe the curative effects,except 1 patient with a little residual shunts,the other patients underwent the procedure successfully without residual shunts and aggravating valvular regurgitation.ConclusionThe homemade ventricular septal occluder is a safe and effective method for treating the transcatheter closure of perimembranous ventricular septal defect.