| 应用酸水解法制备牛蒡苷元的工艺研究 |
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| 引用本文： | 何安宁,何凡,侯蔷,窦德强,康廷国. 应用酸水解法制备牛蒡苷元的工艺研究[J]. 中药研究与信息, 2012, 0(6): 43-45 |
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| 作者姓名： | 何安宁 何凡 侯蔷 窦德强 康廷国 |
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| 作者单位： | 辽宁中医药大学药学院,辽宁大连110066 |
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| 摘 要： | 目的：筛选一种简单制备牛蒡苷元的方法。方法：采用正交试验方法，以HPLC法测定牛蒡苷水解百分比为指标，确定牛蒡子药材的酸水解工艺。结果：以0．5％的盐酸，9倍溶媒量，水解2h，牛蒡苷元的转化率可达到80％以上。结论：此水解工艺合理可行，为牛蒡子的进一步研究提供参考。
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| 关 键 词： | 牛蒡子 牛蒡苷元 酸水解 HPLC 提取工艺 |
Study on the Acidic Hydrolysis Method for the Preparation of Arctigenin |
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| HE An-ning,He Fan,Hou Qiang,DOU De-qiang,KANG Ting-guo. Study on the Acidic Hydrolysis Method for the Preparation of Arctigenin[J]. Research & Information on Traditional Chinese Medicine, 2012, 0(6): 43-45 |
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| Authors: | HE An-ning He Fan Hou Qiang DOU De-qiang KANG Ting-guo |
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| Affiliation: | ( Liaoning University of Traditional Chinese Medicine, Dalian 116600, China) |
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| Abstract: | Objective：To establish a method for Arctigenin preparation. Methods：The extraction conditions were studied by the orthogonal design with the hydrolysis percentage of arctigenin. Results：The optimum conditions were as follows ：adding 9 times amount of 0. 5% （V/V）hydrochloric acid solution and extracting for 2 h. Conclusion： The optimized method is reasonable and feasible for arctigenin preparation from Arctii Fructus. |
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| Keywords: | Arctium lappa Acidic hydrolysis Arctigenin |
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