Recommendations for the Use of Prolonged‐Release Fampridine in Patients with Multiple Sclerosis (MS)期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Recommendations for the Use of Prolonged‐Release Fampridine in Patients with Multiple Sclerosis (MS)

Authors:	Jana Lizrova Preiningerova Ulf Baumhackl Tunde Csepany Adam Czaplinski Florian Deisenhammer Tobias Derfuss Tanja H. Fabjan Franz Fazekas Siegrid Fuchs Eva Havrdova Alenka Horvath Ledinek Zsolt Illes Sasa Sega Jazbec Eleonora Klimova Samuel Komoly Egon Kurca Michael Linnebank Lubomir Lisy Jan Mares Lubica Prochazkova Rozsa Csilla Jarmila Szilasiova Pavel Stourac Radomir Talab Peter Turcani Marta Vachova Laszlo Vecsei David Vodusek Olga Zapletalova Thomas Berger

Affiliation:	1. Department of Neurology and Center for Clinical Neuroscience, Charles University, General Hospital, , Prague, Czech Republic;2. Neurological Practice, , Vienna, Austria;3. Department of Neurology, University of Debrecen, Medical and Health Science Center, , Debrecen, Hungary;4. Department of Neurology, University of Basel, , Basel, Switzerland;5. Department of Neurology, Innsbruck Medical University, , Innsbruck, Austria;6. Department of Neurology, University Hospital Basel, , Basel, Switzerland;7. Department of Neurology, School of Medicine, , Maribor, Slovenia;8. Department of Neurology, Medical University of Graz, , Graz, Austria;9. Department of Neurology, University of Ljubljana, , Ljubljana, Slovenia;10. Department of Neurology, University of Pécs, , Pécs, Hungary;11. Department of Neurology, School of Medicine, , Kosice, Slovak Republic;12. Department of Neurology, School of Medicine, , Martin, Slovak Republic;13. Department of Neurology, University Hospital Zurich, , Zurich, Switzerland;14. Department of Neurology, School of Medicine, , Bratislava, Slovak Republic;15. Department of Neurology, University of Palacky, , Olomouc, Czech Republic;16. Department of Neurology, University Hospital, , Bratislava, Slovak Republic;17. Department of Neurology, Jahn Ferenc Hospital, , Budapest, Hungary;18. Department of Neurology, University Hospital, , Brno, Czech Republic;19. Department of Neurology, University Hospital, , Hradec Kralove, Czech Republic;20. Department of Neurology, Comenius University, , Bratislava, Slovak Republic;21. Department of Neurology, Hospital of Teplice, , Teplice, Czech Republic;22. Department of Neurology, University of Szeged, , Szeged, Hungary;23. Division of Neurology, University of Ljubljana, , Ljubljana, Slovenia;24. Department of Neurology, University Hospital Ostrava, , Ostrava, Czech Republic

Abstract:	Prolonged‐release fampridine (fampridine PR) is a potassium channel blocker that improves conductivity of signal on demyelinated axons in central nervous system. Fampridine PR has been approved to improve speed of walking in patients with multiple sclerosis. This statement provides a brief summary of data on fampridine PR and recommendations on practical use of the medication in clinical practice, prediction, and evaluation of response to treatment and patient management.

Keywords:	Aminopyridines Fampridine Multiple sclerosis Walking

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