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Oxygen Consumption during Surface-Induced Deep Hypothermia under Halothane Anesthesia
Authors:Takeshi Ishitoya  Shigekazu Sato  Giuseppe DiBenedetto  Vittorio Vanini  Hitoshi Mohri  K. Alvin Merendino  David H. Dillard
Affiliation:Division of Cardiothoracic Surgery, Department of Surgery, University Hospital, University of Washington School of Medicine, Seattle, WA.
Abstract:The effect of halothane-100% oxygen anesthesia on oxygen consumption was studied in 10 dogs subjected to surface-induced deep hypothermia with 30 minutes of circulatory arrest. The results were compared with previous oxygen consumption data under ether-100% oxygen anesthesia.Low cardiac output, especially during the rewarming period, low Pa02, and a large arteriovenous oxygen difference during rewarming were significantly different in the halothane group, despite identical oxygen consumption in both groups. These differences could not elucidate the exact cause of postoperative motor disturbances associated with 30 minutes of circulatory arrest in the halothane group. The possibility that there was higher oxygen consumption under halothane anesthesia is discussed.
Keywords:Address reprint requests to Dr. Mohri   Department of Surgery RF-25   University Hospital   Seattle   WA 98195.
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