| 替勃龙联合更年灵治疗围绝经期综合征疗效观察 |
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| 引用本文： | 侯雯莅,王新英. 替勃龙联合更年灵治疗围绝经期综合征疗效观察[J]. 河北医药, 2009, 31(8): 920-922 |
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| 作者姓名： | 侯雯莅 王新英 |
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| 作者单位： | 河北省保定市妇幼保健院妇保科,071000;河北省保定市妇幼保健院妇保科,071000 |
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| 摘 要： | 目的了解替勃龙联合更年灵胶囊治疗围绝经期综合征的临床疗效和安全性。方法将我院120例患者随机分成2组各60例：观察组口服替勃龙1．25mg，1次／d，配合更年灵每次1粒，3次／d。对照组口服替勃龙1．25mg，1次／d。3个月为1疗程。治疗前后B型超声了解子宫内膜情况，检查肝、肾功能、血清B水平，乳腺情况。Kupperman评分每月1次。结果2组用药后围绝经期症状均明显改善。观察组控制围绝经期症状的疗效优于对照组（P〈0．05），且不良反应低。治疗后血清E2水平观察组高于对照组（P〈0．05）。子宫内膜厚度治疗前后无明显变化（P〉0．05）。结论小剂量替勃龙联合更年灵胶囊能有效地控制围绝经期症状且安全可靠。
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| 关 键 词： | 替勃龙 更年灵 治疗 围绝经期综合征 |
Clinical observation of the therapeutic effect of tibolone combined with gengnianling on perimenopausal syndrome |
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| HOU Wenli,WANG Xinying. Clinical observation of the therapeutic effect of tibolone combined with gengnianling on perimenopausal syndrome[J]. Hebei Medical Journal, 2009, 31(8): 920-922 |
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| Authors: | HOU Wenli WANG Xinying |
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| Affiliation: | HOU Wenli,WANG Xinying.Baoding Maternal , Children Health Hospital,Hebei,Baoding 071000,China |
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| Abstract: | Objective To observe the therapeutic effect and safety of tibolone combined with gengnianling capsule on perimenopausal syndrome.Methods 120 patients with perimenopausal syndrome were randomly divided into two groups who were enrolled from Dec 2006 to Dec 2007 in our hospital.The 60 patients received tibolone 1.25 mg once a day combined with gengnianling capsule 1 pill each time,3 times a day.The other 60 patients received tibolone 1.25 mg once a day,with a treatment course of 3 months for both groups.The t... |
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| Keywords: | tibolone gengnianling therapy perimenopausal syndrome |
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