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Peptidergic Correction of the Effect of Acute Hypobaric Hypoxia in Pregnant Rats on Progeny
Authors:M. V. Maslova  K. S. Zemlyanskii  M. V. Shkol'nikova  A. S. Maklakova  Ya. V. Krushinskaya  N. A. Sokolova  I. P. Ashmarin
Affiliation:(1) Department of Human and Animal Morphology, Biological Faculty, M. V. Lomonosov Moscow State University, Russia
Abstract:Acute hypobaric hypoxia of pregnant rats led to a significant delay in body weight gain, growth and time of eye opening in newborn rat pups which was paralleled by behavioral changes. Preventive intranasal instillations of peptide mixture (semax and beta-casomorphine-7) to pregnant females prevented the effect of hypoxia on the progeny.
Keywords:pregnant rats  hypoxia  effect on progeny  semax  b-casomorphine
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