| 毒理基因组学与DNA微阵列技术的应用 |
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| 引用本文： | 曹佳,周紫垣,方福德,杨梦甦,胡绍燊,游力.毒理基因组学与DNA微阵列技术的应用[J].中国药理学与毒理学杂志,2000,14(5):336-340. |
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| 作者姓名： | 曹佳 周紫垣 方福德 杨梦甦 胡绍燊 游力 |
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| 作者单位： | [1]第三军医大学预防医学系分子毒理学实验室,重庆 [2]中国医学科学院基础所医学分子生物学国？ |
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| 基金项目： | 香港城市大学 RCP资助项目!(2 0 0 0 - 8) |
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| 摘 要： | 近几年来 DNA微阵列和 DNA芯片技术得到了迅速发展 ,并开始应用于毒理学研究 ,本文介绍了微阵列技术如何与毒理学研究相结合并应用于危险度评估 ,并形成一个新的研究领域毒理基因组学
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| 关 键 词： | 毒理基因组学 DNA微阵列 DNA芯片 |
| 收稿时间： | 2000-8-9 |
Toxicogenomics and applications of DNA microarrays |
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| CAO Jia, ZHOU Zi-Yuan, FANG Fu-De, YANG Meng-Su, HU Shao-Shen, YOU Li.Toxicogenomics and applications of DNA microarrays[J].Chinese Journal of Pharmacology and Toxicology,2000,14(5):336-340. |
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| Authors: | CAO Jia ZHOU Zi-Yuan FANG Fu-De YANG Meng-Su HU Shao-Shen YOU Li |
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| Institution: | (1. Molecular Toxicology Laboratory, the Third Military Medical University, Chongqing 400038, China; 2. The Key National Laboratory of Medical Molecular Biology, Institute of Basic Medical, Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China; 3. Applied Research Centre for Genomic Technologies, Department of Biology and Chemistry, City University of Hong Kong, Hong Kong; 4. Chemical Industry Institute of Toxicology, NC 27709, USA) |
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| Abstract: | In the past few years,the DNA microarrays and DNA chip techniques were developed very fast,and they were started to use in toxicology area.In this article,we introduce the microarray techniques how to incorporated into toxicology studies and risk assessment,and finally to produce a new toxicological research subdiscipline - toxi- cogenomics. |
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| Keywords: | toxicogenomics DNA microar- rays DNA chips |
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