| 浅述早期糖尿病肾病及相关炎症因子的变化 |
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| 引用本文： | 孙志芬,邢喜芝,王彦敏,刘秀春,彭美华.浅述早期糖尿病肾病及相关炎症因子的变化[J].中国中医药现代远程教育,2011,9(19):83-84. |
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| 作者姓名： | 孙志芬 邢喜芝 王彦敏 刘秀春 彭美华 |
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| 作者单位： | 河北省沧州和平医院内科,沧州,061001 |
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| 摘 要： | 目的观察吡格列酮治疗早期糖尿病肾病的疗效。方法 53例门诊及住院患者随机分配到治疗组及对照组。所有患者给予低盐、优质蛋白、糖尿病饮食,糖尿病教育,定期随访监督指导,监测血糖、血压稳定后1周,对照组继续维持治疗,吡格列酮组应用吡格列酮胶囊30mg,每日1次,全部病例观察6周。结果治疗后2组中24h UAER和TNF-α较治疗前有明显下降(P<0.05)、脂联素水平较前升高(P<0.05);吡格列酮组治疗后FBG和24hUAER下降更多,脂联素升高的更多(P<0.05)。结论表明吡格列酮具有保护肾脏的作用。
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| 关 键 词： | 糖尿病肾病 吡格列酮 肿瘤坏死因子-α 脂联素 中西医结合疗法 |
Pioglitazone Treatment Early Diabetic Nephropathy and Related Inflammation Factors Change |
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| Sun Zhifen Shao Peng Xing Xizhi Wang Yanmin.Pioglitazone Treatment Early Diabetic Nephropathy and Related Inflammation Factors Change[J].Chinese Medicine Modern Distance Education of China,2011,9(19):83-84. |
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| Authors: | Sun Zhifen Shao Peng Xing Xizhi Wang Yanmin |
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| Institution: | Sun Zhifen Shao Peng Xing Xizhi Wang Yanmin Department of Intnernal Medicine,Peace Hospital,Cangzhou 061001,China |
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| Abstract: | Objective Observe the curative effect of Pioglitazone treatment early diabetic nephropathy..Methods 53 cases of clinic and hospitalized patients were randomly assigned to the treatment group and control group.All of the patients given low salt,high grade protein,diabetes diet,diabetes education,regular follow-up supervision and guidance,Monitor blood glucose,blood pressure stabilize 1 week,The control group to maintain treatment,Pioglitazone group:Pioglitazone capsule 30 mg,every day once,All cases observat... |
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| Keywords: | Pioglitazone Diabetic nephropathy TNF-α Adiponectin |
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