| 黄龙止咳口服液质量标准研究 |
| |
| 引用本文： | 丁红梓,谈瑄忠. 黄龙止咳口服液质量标准研究[J]. 中国中医药信息杂志, 2011, 18(10): 60-62. DOI: 10.3969/j.issn.1005-5304.2011.10.023 |
| |
| 作者姓名： | 丁红梓 谈瑄忠 |
| |
| 作者单位： | 1. 南京市胸科医院,江苏南京,210029
2. 南京中医药大学第三附属医院,江苏南京,210001 |
| |
| 摘 要： | 目的建立黄龙止咳口服液的质量标准。方法采用薄层色谱法鉴别麻黄、前胡、地龙;采用高效液相色谱法测定盐酸麻黄碱的含量,流动相为乙腈-0.1%磷酸（4∶96）,检测波长为207 nm。结果薄层色谱法可检出麻黄、前胡、地龙,斑点清晰,阴性对照无干扰,专属性强。盐酸麻黄碱在0.1023～2.045μg范围内线性良好（r=0.9999）,平均加样回收率为103.05%,RSD=1.65%。结论本方法简便、准确、重复性好,可用于黄龙止咳口服液的质量控制。
|
| 关 键 词： | 黄龙止咳口服液 盐酸麻黄碱 薄层色谱法 高效液相色谱法 |
Study on Quality Standard for Huanglong Cough Liquid |
| |
| DING Hong-zi,TAN Xuan-zhong. Study on Quality Standard for Huanglong Cough Liquid[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2011, 18(10): 60-62. DOI: 10.3969/j.issn.1005-5304.2011.10.023 |
| |
| Authors: | DING Hong-zi TAN Xuan-zhong |
| |
| Affiliation: | DING Hong-zi1,TAN Xuan-zhong2(1.The Chest Hospital of Nanjing City,Nanjing 210029,China,2.The Third Affiliated Hospital of Nanjing University of TCM,Nanjing 210001,China) |
| |
| Abstract: | Objective To establish the quality standard for Huanglong Cough Liquid.Methods Herba Ephedrae,Radix Peucedani and Pheretima were determined by TLC.The content of ephedrine hydrochloride was determined by HPLC,with the mobile phase of acetonitrile-0.1% phosphatic water（4∶96） and the detection wavelength of 207 nm.Results Herba Ephedrae,Radix Peucedani and Pheretima could be identified by TLC,the spots were clear with no interference.The quantitative method of ephedrine hydrochloride showed a good linearity in the range of 0.102 3-2.045 μg（r=0.999 9）.The average recovery of Peoniflorin was 103.05%,and RSD was 1.65%.Conclusion The method is simple,accurate and reproducible.It can be used effectively for the quality control of Huanglong Cough Liquid. |
| |
| Keywords: | Huanglong Cough Liquid ephedrine hydrochloride TLC HPLC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
